Liver damage due to medication |
 |  | Translated by Marta Campbell |
 |
10.06.2025 12:00 Uhr |
According to the AdkÄ, there are risks of liver damage from medication. The commission cites older patients as being more at risk, partly because they often take several medications. The risk for women doubles from the age of 50. In people of white skin colour, the combination of amoxicillin and clavulanic acid in particular damages the liver; in people of Afroamerican origin, it is cotrimoxazole. Other risk factors for liver damage caused by certain medications, such as the antirheumatic and cytostatic drug methotrexate, are obesity, diabetes, alcohol and viral hepatitis. In addition, genetic factors influence the enzymes involved in the breakdown of drugs in the liver and therefore their effectiveness.
Doctors diagnose liver damage using a process of exclusion, taking into account a detailed history of the medication and dietary supplements taken by the patient. In addition, typical liver blood values are determined, as well as serum albumin and the INR (International Normalized Ratio). A reduced serum albumin value may be due to a synthesis defect in the liver. The Quick or INR value indicates blood clotting disorders in the liver. A reduced value indicates impaired function.
| Deutsch/German | Englisch/English |
|---|---|
| Antidot | Antidote |
| Appetitlosigkeit | Loss of appetite |
| Blutgerinnung | Blood clotting |
| Blutwerte | Blood values |
| Erbrechen | Vomiting |
| Fasten | Fasting |
| Fieber | Fever, Temperature |
| Gelbsucht | Jaundice |
| Gelenkschmerzen | Joint pain |
| Juckreiz | Itching |
| Leber | Liver |
| Leberschaden | Liver damage |
| Mangelernährung | Malnutrition |
| Nahrungsergänzungsmittel | Dietary supplements |
| Phytopharmaka | Phytopharmaceuticals |
| Regeneration | Regeneration |
| Serumalbumin | Serum albumin |
| Toxizität | Toxicity |
| Überdosierung | Overdose |
| Verfärbung | Discoloration |
