Mechanisms not understood

Systematic reviews have also shown that there is no evidence for the benefit of inhaled glucocorticoids, bronchodilators such as salbutamol or antibiotics for post-infectious cough. Instead, these therapies are associated with adverse effects and high costs. They put a strain on supply chains and this can mean that inhalers are no longer sufficiently available for patients who really need them. Metered-dose inhalers also pollute the environment due to the propellants used. Scientists from Switzerland are currently investigating whether a five-day treatment with oral glucocorticoids brings patient-relevant benefits compared to placebo. There are already indications that the medication could improve cough-related quality of life and reduce the duration and intensity of post-infectious coughs.

The efficacy of centrally acting antitussives such as codeine and dextromethorphan in post-infectious coughs has not been proven. Cough suppressants suppress the urge to cough, but should only be taken for a short time to avoid side effects and addiction. Phytopharmaceuticals can supportively reduce the symptoms and promote healing. Thyme and ivy extract have anti-inflammatory and expectorant properties and are traditionally used to relieve coughs. Although the scientific evidence is not as good as for other preparations, many patients report an improvement in symptoms.

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